Design Methods >>>

Design Methods - General:

• Does each experiment/method correspond to one of the specific aims, and state in the same order.
• Follow a logical sequence.
• Offer a timetable showing how and when.
• Use flow charts and decision trees to show paths of design/methods and how they will progress.
• Estimate what you expect to accomplish each year and state foreseeable delays.
• Describe any hazardous procedures, situations, or materials, as well as appropriate precautions.
• Include supporting data.
• Include sufficient detail to show understanding and can handle the research.
• Cite references wherever possible.

Design Methods - Approach:

• State the expected outcome of your research.
• List each step in the same order as specific aims, linking steps to the aims so reviewers can see how you will achieve them.
• Show why each experiment/step is important or how it is relevant to the hypothesis/project.
• Are the steps/experiments in a logical sequence, flowing from one to another with clear end points.
• Offer a timeline.
• Justify choice of methods in detail.
• Outline methods in detail.
• Support methods with data.
• Provide solutions for potential problems.
• Address difficulties you may encounter; show you can handle them, propose solutions and alternatives.
• Estimate how much you expect to accomplish each year of the grant and state any potential delays.
• Use enough detail (keep in mind page limitations).
• Anticipate reviewers' questions about the feasibility of what you propose, e.g., how you will gain access to equipment or study populations.

Design Methods - Results:

• Show you are aware of the limits to and value of the kinds of results you expect
• Convince reviewers you will be able to interpret results
• Define the criteria for evaluating the success or failure of a specific test
• State the limits you will observe in interpreting results

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